Enantioselective desymmetrization of meso bicyclic hydrazines: a novel approach to the asymmetric synthesis of polysubstituted amino cyclopentanic cores.

作者: A. Pérez Luna , M.-A. Ceschi , M. Bonin , L. Micouin , H.-P. Husson

DOI: 10.1021/JO011190E

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摘要: Catalytic asymmetric hydroboration can be successfully applied to meso bicyclic hydrazines. The resulting alcohols are of great synthetic interest and lead in a straightforward manner cyclopentanic diamino with good enantiomeric purity.

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