Investigating the Role of Micromammals in the Ecology of Coxiella burnetii in Spain.

摘要: Coxiella burnetii, the causal agent of human Q fever and animal Coxiellosis, is a zoonotic infectious bacterium with complex ecology that results from its ability to replicate in multiple (in)vertebrate host species. Spain notifies highest number cases ECDC annually wildlife plays relevant role C. burnetii country. However, whole picture hosts incomplete, so this study seeks better understand micromammals Spleen samples 816 10 species 130 vaginal swabs Microtus arvalis were analysed by qPCR detect infection shedding, respectively. The 9.7% spleen positive. prevalence (10.8%) was found arvalis, which DNA also detected 1 (0.8%) analysed. Positive Apodemus sylvaticus (8.7%), Crocidura russula (7.7%) Rattus rattus (6.4%). genotyped coupling PCR reverse line blotting genotype II+ strain identified for first time one positive M. whereas only partial could be obtained rest samples. Acute diagnosed researchers participated study, it presumably linked handling. are consistent previous findings suggesting can infected burnetii. Our additionally suggest may potential sources trace back origin Coxiellosis Europe.