Outcomes After Stereotactic Body Radiotherapy or Radiofrequency Ablation for Hepatocellular Carcinoma
作者： Daniel R. Wahl , Matthew H. Stenmark , Yebin Tao , Erqi L. Pollom , Elaine M. Caoili
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摘要: PurposeData guiding selection of nonsurgical treatment hepatocellular carcinoma (HCC) are lacking. We therefore compared outcomes between stereotactic body radiotherapy (SBRT) and radiofrequency ablation (RFA) for HCC.Patients MethodsFrom 2004 to 2012, 224 patients with inoperable, nonmetastatic HCC underwent RFA (n = 161) 249 tumors or image-guided SBRT 63) 83 tumors. applied inverse probability weighting adjust imbalances in assignment. Freedom from local progression (FFLP) toxicity were retrospectively analyzed.ResultsRFA groups similar respect number lesions treated per patient, type underlying liver disease, tumor size (median, 1.8 v 2.2 cm maximum diameter; P .14). However, the group had lower pretreatment Child-Pugh scores (P .003), higher alpha-fetoprotein levels .04), a greater prior liver-directed treatments < .001). One- 2-year FFLP RF...
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