Strategies to meet the need for long-term data

摘要: Chronic diseases afflict patients for many years, often to the end of life, and there is increasing need estimating lifelong risk evaluating effects treatment in long term. Yet recommendations are most frequently based on findings from randomized clinical trials lasting only a few years. There therefore clear much longer term data, here we present advantages disadvantages strategies, including use long-term posttrial follow-up, prospective cohort studies, registry databases, administrative databases. We also emphasize cost-effectiveness studies. One promising strategies comes linkage data gathered through ever-expanding pool databases worldwide with other sources, forms observational study.