Role of Antibody to S100 Protein in Diagnostic Pathology

摘要: Normal tissues and various tumors were examined for S100 protein, using anti-S100 protein antiserum, in an immunoperoxidase reaction. Among normal tissues, addition to the previously reported presence of some neurons, glial, Schwann cells nervous system, melanocytes Langerhans skin, interdigitating reticulum lymph nodes, chondrocytes, we demonstrated it myoepithelial ducts sweat glands, salivary breast, serous glands lung, fetal neuroblasts, sustentacular adrenal medulla. neoplasms, has been neurogenic tumors, melanomas, neuroblastomas; have mixed gland histiocytosis X, pleomorphic adenomas gland, medullary carcinomas bronchioloalveolar pheochromocytomas, teratomas ovary, cartilage (enchondromas, osteochondromas, chondrosarcomas). With producing a progenitor cell was identified, indicating that demonstration confirmed their origin.