The central representation of an aversive event maintains the opioid and nonopioid forms of analgesia.

摘要: Exposure to an aversive event, such as shock, can elicit either opioid or nonopioid analgesia in rats. We suggest that the central representation of event working memory activates both forms analgesia. formalize this basic hypothesis by coupling it with a current model animal learning and memory, SOP (Wagner, 1981). is designed capture standard operating procedures govern systems. Our application suggests manipulations which disrupt maintenance information should alter magnitude time course Three experiments are reported support our proposal. Experiment 1 showed decays more rapidly if displaced from presenting postshock distractor. 2 demonstrated distractor alters 3 pharmacologically disrupting administering high dose pentobarbital, prevents mild shock inducing strong change pain reactivity. Implications results discussed.