Synthesis of β -prolinols via [3+2] cycloaddition and one-pot programmed reduction: Valuable building blocks for polyheterocycles
作者： Jundong Li , Na Lin , Lei Yu , Yandong Zhang
DOI: 10.1016/J.TETLET.2016.11.035
关键词:
摘要: Abstract A novel two-step synthesis of multisubstituted β-prolinols has been developed, featuring a [3+2] cycloaddition azomethine ylides and programmed reduction triggered by the combination borane lithium aluminum hydride (LAH). β-Prolinols are shown to be valuable building blocks for polyheterocycles.
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