Ecology, Epidemiology and Human Health Implications of Avian Influenza Virus Infections

摘要: Avian influenza (Al) represents one of the greatest concerns for public health that has emerged from animal reservoir in recent times. AI, its highly path ogenic form (HPAI), been known to veterinary community since end 19th century, when an Italian scientist. Edoardo Perroncito, reported what is believed be first documented evidence “fowl plague” as a distinct disease. However, over 100 years, HPAI proved poultry disease rare occurrence that, most cases, affected irrelevant number birds. Generally speaking, it was either self-limiting or controlled efficiently through application measures aimed evadicating infection area. At approximately turn millennium, however, sharp increase outbreaks AI occurred. It calculated impact on industry increased 100-fold, with 23 million birds 40-year period between 1959 and 1998 200 1999 2004 (Capua Alexander 2004).