Recombinant soluble CR1 suppressed complement activation, inflammation, and necrosis associated with reperfusion of ischemic myocardium.

作者: Leppo Mk , Weisman Hf , Boyle Mp , Weisfeldt Ml , Bartow T

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摘要: In summary, conversion of wild-type CR1 to a soluble form (sCR1) creates a potent inhibitor of complement activation by both the classical and alternative pathways by inhibiting the C3/…

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