Impact of Implementing B-RSTTM to Screen for Hereditary Breast and Ovarian Cancer on Risk Perception and Genetic Counseling Uptake Among Women in an Academic Safety Net Hospital.

作者: Karen Wernke , Cecelia Bellcross , Sheryl Gabram , Nadia Ali , Christine Stanislaw

DOI: 10.1016/J.CLBC.2019.02.014

关键词:

摘要: Abstract Background Lower socioeconomic status is strongly associated with decreased perception of cancer risk. Fewer low women than expected currently access genetic services from which they may benefit. Patients and Methods We screened presenting for a screening mammogram at safety net academic hospital using the Breast Cancer Genetics Referral Screening Tool Version 3.0 (B-RSTTM), an online tool designed to identify individuals potentially risk hereditary breast ovarian cancer. Participants either positive (high risk) or negative (moderate were offered counseling appointments. used brief survey evaluate change in before after B-RSTTM, appointment, if applicable. Barriers accepting appointments assessed when participants declined. Results Of 126 participants, 91 (72.2%) negative-average risk, 13 (10.3%) negative-moderate 22 (17.5%) positive. those who negative-moderate, 24 (68.6%) expressed interested 19 (79.2%) scheduled. Four scheduled (21.1%) completed appointment. found significant difference number rated their correctly on post-test between groups self-rated as low, moderate, high Those perceived themselves most likely rate (P  Conclusion showed that B-RSTTM was effective identifying increased ovarian cancer.

参考文章(34)
Beth Anderson, Jennifer McLosky, Elizabeth Wasilevich, Sarah Lyon-Callo, Debra Duquette, Glenn Copeland, Barriers and Facilitators for Utilization of Genetic Counseling and Risk Assessment Services in Young Female Breast Cancer Survivors Journal of Cancer Epidemiology. ,vol. 2012, pp. 298745- 298745 ,(2012) , 10.1155/2012/298745
José A Pagán, Cynthia J Brown, David A Asch, Katrina Armstrong, Elena Bastida, Carmen Guerra, None, Health literacy and breast cancer screening among Mexican American women in South Texas. Journal of Cancer Education. ,vol. 27, pp. 132- 137 ,(2012) , 10.1007/S13187-011-0239-6
Suzanne M. O'Neill, June A. Peters, Victor G. Vogel, Eleanor Feingold, Wendy S. Rubinstein, Referral to cancer genetic counseling: Are there stages of readiness? American Journal of Medical Genetics Part C: Seminars in Medical Genetics. ,vol. 142C, pp. 221- 231 ,(2006) , 10.1002/AJMG.C.30109
Amy P.M. Finch, Jan Lubinski, Pål Møller, Christian F. Singer, Beth Karlan, Leigha Senter, Barry Rosen, Lovise Maehle, Parviz Ghadirian, Cezary Cybulski, Tomasz Huzarski, Andrea Eisen, William D. Foulkes, Charmaine Kim-Sing, Peter Ainsworth, Nadine Tung, Henry T. Lynch, Susan Neuhausen, Kelly A. Metcalfe, Islay Thompson, Joan Murphy, Ping Sun, Steven A. Narod, Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation Journal of Clinical Oncology. ,vol. 32, pp. 1547- 1553 ,(2014) , 10.1200/JCO.2013.53.2820
Virginia A Moyer, US Preventive Services Task Force*, None, Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement. Annals of Internal Medicine. ,vol. 160, pp. 271- 281 ,(2014) , 10.7326/M13-2747
Teresa Doksum, Sharon A. Metz, Gail Geller, Barbara A. Bernhardt, Participation in Breast Cancer Susceptibility Testing Protocols: Influence of Recruitment Source, Altruism, and Family Involvement on Women’s Decisions Cancer Epidemiology, Biomarkers & Prevention. ,vol. 8, pp. 377- 383 ,(1999)
Sining Chen, Giovanni Parmigiani, Meta-analysis of BRCA1 and BRCA2 penetrance Journal of Clinical Oncology. ,vol. 25, pp. 1329- 1333 ,(2007) , 10.1200/JCO.2006.09.1066
Susan M Domchek, Tara M Friebel, Christian F Singer, D Gareth Evans, Henry T Lynch, Claudine Isaacs, Judy E Garber, Susan L Neuhausen, Ellen Matloff, Rosalind Eeles, Gabriella Pichert, Laura Van t’veer, Nadine Tung, Jeffrey N Weitzel, Fergus J Couch, Wendy S Rubinstein, Patricia A Ganz, Mary B Daly, Olufunmilayo I Olopade, Gail Tomlinson, Joellen Schildkraut, Joanne L Blum, Timothy R Rebbeck, None, Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality JAMA. ,vol. 304, pp. 967- 975 ,(2010) , 10.1001/JAMA.2010.1237
Alanna Kulchak Rahm, Anna Sukhanova, Jennifer Ellis, Judy Mouchawar, Increasing utilization of cancer genetic counseling services using a patient navigator model. Journal of Genetic Counseling. ,vol. 16, pp. 171- 177 ,(2007) , 10.1007/S10897-006-9051-6
C. Lerman, E. Lustbader, B. Rimer, M. Daly, S. Miller, C. Sands, A. Balshem, Effects of Individualized Breast Cancer Risk Counseling: a Randomized Trial Journal of the National Cancer Institute. ,vol. 87, pp. 286- 292 ,(1995) , 10.1093/JNCI/87.4.286