作者: Nameeta Shah , MichaelV Teplitsky , Simon Minovitsky , LenA Pennacchio , Philip Hugenholtz
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摘要: Background Recent advances in sequencing technologies promise to provide a better understanding of the genetics human disease as well evolution microbial populations. Single Nucleotide Polymorphisms (SNPs) are established genetic markers that aid identification loci affecting quantitative traits and/or wide variety eukaryotic species. With today's technological capabilities, it has become possible re-sequence large set appropriate candidate genes individuals with given an attempt identify causative mutations. In addition, SNPs have been used extensively efforts study populations, and recent application random shotgun environmental samples enables more extensive SNP analysis co-occurring co-evolving The program is available at http://genome.lbl.gov/vista/snpvista[1].