Oestrogen Receptors, Clinical Features and Prognosis in Stage III Breast Cancer

作者: John F. Stewart , Roger J.B. King , Peter J. Winter , David Tong , John L. Hayward

DOI: 10.1016/0277-5379(82)90135-3

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摘要: Abstract One hundred and twenty-four patients with stage III breast cancer who had oestrogen receptor analyses (ER) performed on primary tumour were studied. For operable disease (T 3a ; N 0.1 , M 0 ), ER-negative (ER fmol / mg cytosol protein) tumours a shorter duration of symptoms, but no other differences observed at presentation. In inoperable 3b,4 or any T, 2,3 ) there in the clinical characteristics that rendered between those ER+ ER− tumours. The median disease-free interval (DFI) uninvolved axillary nodes was significantly longer ( P 27.5 months compared to effect ER status prognosis demonstrated. These results suggest content may be prognostic variable cancer, further studies similar methods initial treatment are needed confirm this. Patients should considered separately from locally advanced view significant their survival prospects.

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