Genetic Analysis of Quantitative Phenotypes in AD and MCI: Imaging, Cognition and Biomarkers
作者： Li Shen , , Paul M. Thompson , Steven G. Potkin , Lars Bertram
DOI: 10.1007/S11682-013-9262-Z
关键词:
摘要: The Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI), formally established in 2009, aims to provide resources and facilitate research related genetic predictors multidimensional Alzheimer' sd isease (AD)-related phenotypes. Here, we a systematic review studies published between 2009 2012 where either ADNI APOE genotype or genome-wide associ- ation study (GWAS) data were used. We synthe- size associations with disease status quanti- tative endophenotypes including structural Data used preparation this article obtained from (ADNI) database (adni.loni.ucla.edu). As such, many investigators within con- tributed design implementation and/or provided but did not participate analysis writing report. A complete listing can be found at: http://adni.loni.ucla.edu/
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