Environmental Substances Associated with Osteoporosis-A Scoping Review.
作者： Hanna Tolonen , Marike Kolossa-Gehring , Rosa Lange , Hanna Elonheimo
关键词:
摘要: Introduction: Osteoporosis is a disease having adverse effects on bone health and causing fragility fractures. affects approximately 200 million people worldwide, nearly 9 fractures occur annually. Evidence exists that, in addition to traditional risk factors, certain environmental substances may increase the of osteoporosis. Methods: The European Human Biomonitoring Initiative (HBM4EU) joint program coordinating advancing human biomonitoring Europe. HBM4EU investigates citizens’ exposure several their plausible aiming contribute policymaking. In HBM4EU, 18 priority or substance groups were selected. For each, scoping document was prepared summarizing existing knowledge effects. This review based these chemical-specific documents complementary literature review. Results: A possible link between osteoporosis body burden heavy metals, such as cadmium (Cd) lead (Pb), industrial chemicals phthalates per- poly-fluoroalkyl (PFASs) identified. Conclusions: shows that be related an effect. Nevertheless, more epidemiological research relationship needed. Study results are incoherent, pervasive studies regarding chemical lacking.
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