Uncovering the structure-function relationship in spider silk

作者: Jeffery L. Yarger , Brian R. Cherry , Arjan van der Vaart

DOI: 10.1038/NATREVMATS.2018.8

关键词:

摘要: All spiders produce protein-based biopolymer fibres that we call silk. The most studied of these silks is spider dragline silk, which is very tough and relatively abundant compared with other types of spider silks. Considerable research has been devoted to understanding the relationship between the molecular structure and mechanical properties of spider dragline silks. In this Review, we overview experimental and computational studies that have provided a wealth of detail at the molecular level on the highly conserved repetitive core and …

参考文章(157)
Jun Ashida, Kosuke Ohgo, Kohei Komatsu, Ayumi Kubota, Tetsuo Asakura, Determination of the torsion angles of alanine and glycine residues of model compounds of spider silk (AGG)(10) using solid-state NMR methods. Journal of Biomolecular NMR. ,vol. 25, pp. 91- 103 ,(2003) , 10.1023/A:1022220428948
Franz Hagn, A structural view on spider silk proteins and their role in fiber assembly. Journal of Peptide Science. ,vol. 18, pp. 357- 365 ,(2012) , 10.1002/PSC.2417
Fritz Vollrath, David P. Knight, Liquid crystalline spinning of spider silk. Nature. ,vol. 410, pp. 541- 548 ,(2001) , 10.1038/35069000
Erly Sintya, Parvez Alam, None, Self-assembled semi-crystallinity at parallel β-sheet nanocrystal interfaces in clustered MaSp1 (spider silk) proteins. Materials Science and Engineering: C. ,vol. 58, pp. 366- 371 ,(2016) , 10.1016/J.MSEC.2015.08.038
J.E. Trancik, J.T. Czernuszka, F.I. Bell, C. Viney, Nanostructural features of a spider dragline silk as revealed by electron and X-ray diffraction studies Polymer. ,vol. 47, pp. 5633- 5642 ,(2006) , 10.1016/J.POLYMER.2005.01.110
Fritz Vollrath, David Porter, Chris Holland, There are many more lessons still to be learned from spider silks Soft Matter. ,vol. 7, pp. 9595- 9600 ,(2011) , 10.1039/C1SM05812F
F. H. C. CRICK, ALEXANDER RICH, Structure of Polyglycine II Nature. ,vol. 176, pp. 780- 781 ,(1955) , 10.1038/176780A0
Mingying Yang, Yasumoto Nakazawa, Kazuo Yamauchi, David Knight, Tetsuo Asakura, Structure of model peptides based on Nephila clavipes dragline silk spidroin (MaSp1) studied by 13C cross polarization/magic angle spinning NMR. Biomacromolecules. ,vol. 6, pp. 3220- 3226 ,(2005) , 10.1021/BM050550V