Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial
作者： Sina Brückner , Selidji T Agnandji , Stefan Berberich , Emmanuel Bache , José F Fernandes
DOI: 10.1371/JOURNAL.PNTD.0003768
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摘要: Background Helminth infections are a major public health problem, especially in the tropics. Infected individuals have an altered immune response with evidence that antibody to vaccination is impaired. Hence, treatment of helminth before may be simple intervention improve vaccine immunogenicity. In present study we investigated whether single-dose antihelminthic influences responses seasonal influenza primary school children living Gabon, Central Africa.
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