作者: Theodore Warkentin , Andreas Greinacher
DOI: 10.1503/CMAJ.210637
关键词:
摘要: Heparin-induced thrombocytopenia (HIT) is an adverse prothrombotic disorder caused by immune response to complexes of platelet factor 4 and polyanions. The clinical relevance HIT results from the wide use heparin, which reason that absolute number patients affected high. currently most frequent immune-mediated drug reaction affecting blood cells.