The current-voltage relation of a pore and its asymptotic behavior in a Nernst-Planck model

作者: Nicolae Marius Bîrlea , Sînziana Iulia Bîrlea

DOI: 10.5617/JEB.296

关键词:

摘要: A model for current-voltage nonlinearity and asymmetry is a good starting point explaining the electrical behavior of nanopores in synthetic or biological membranes. Using Nernst-Planck model, we found three behaviors current density membrane's pore as function voltage: quasi-ohmic, slow rising linear at low voltages, nonlinear intermediate non-ohmic, fast large voltages. The slope quasi-ohmic depends mainly on height energy barrier inside pore, w , through an exponential term, e . magnitude non-ohmic controlled by potential gradient entrance, / r relation asymmetric if ion's has triangular profile. only two assumed parameters, height, relative size entrance region which useful feature fitting interpreting experimental data.

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