Neutron capture therapy beams at the MIT Research Reactor.
作者： J. R. Choi , S. D. Clement , O. K. Harling , R. G. Zamenhof
DOI: 10.1007/978-1-4684-5802-2_15
关键词:
摘要: Several neutron beams that could be used for capture therapy at MITR-II are dosimetrically characterized and their suitability the treatment of glioblastoma multiforme other types tumors described. The studied are: 1) those filtered by various thicknesses cadmium, D2O, 6Li, bismuth; 2) epithermal achieved filtration with aluminum, sulfur, bismuth. Measured dose vs. depth data presented in polyethylene phantom references to what can expected brain. results indicate both useful therapy. first type have good therapeutic advantage depths (approximately 5 cm) excellent in-phantom ratios background dose. Such would treating located relatively shallow On hand, second superior (greater than 6 ratios. beams, when along bilateral irradiation schemes, able treat any Numerical examples these using RBEs, fractionated-dose delivery, unilateral, paper. Finally, additional plans further beam development discussed.
springer.com
osti.gov
sci-hub.st 参考文章(6)
S F Mughabghab, N E Holden, M Divadeenam, Neutron cross sections Academic Press. ,(1981)
S. F. Mughabghab, M. Divadeenam, N. E. Holden, Neutron resonance parameters and thermal cross sections ,(1981)
R. G. Zamenhof, S. D. Clement, O. K. Harling, J. F. Brenner, D. E. Wazer, H. Madoc-Jones, J. C. Yanch, Monte Carlo Based Dosimetry and Treatment Planning for Neutron Capture Therapy of Brain Tumors Neutron Beam Design, Development, and Performance for Neutron Capture Therapy. ,vol. 54, pp. 283- 305 ,(1990) , 10.1007/978-1-4684-5802-2_22
Frank Herbert Attix, Introduction to Radiological Physics and Radiation Dosimetry ,(1991)
R.S. Caswell, J.J. Coyne, M.L. Randolph, Kerma factors of elements and compounds for neutron energies below 30 MeV The International Journal of Applied Radiation and Isotopes. ,vol. 33, pp. 1227- 1262 ,(1982) , 10.1016/0020-708X(82)90246-0
W. Zobel, Experimental determination of corrections to the neutron activation of gold foils exposed in water Oak Ridge National Laboratory operated by Union Carbide Corporation for the U.S. Atomic Energy commission. ,(1963) , 10.2172/4710823