Endogenous Opiates and Exercise-Related Hypoalgesia

摘要: Endogenous opiates, endorphins and enkephalins, influence processes within the body including pain, cardiac function, blood pressure, cellular growth, immunity, glucose regulation. Opiates discharged inside CNS stay this compartment, whereas those in circulation primarily arise from anterior pituitary gland, but some are released immune cells peripheral nerves. Generally, acute aerobic resistance exercises of sufficient intensity volume have been reported to induce a hypoalgesia response. This response appears be related various pathways involved with other neurotransmitters that alter perceptions pain. Alteration pain thresholds may transiently occur exercise. Changes using new technologies suggest beta-endorphins (βE) brain signaling. Furthermore, elevation βE modifies responses assist regulation during Limited research on enkephalins exercise has conducted, results equivocal. A limited number studies enkephalin increases certain regions brain. However, discrepancies endurance training occurred. Clearly more is needed dealing endogenous opioids exercise, especially help elucidate how influences function.