作者: Rodolfo Aramayo , Robert L Metzenberg
DOI: 10.1016/S0092-8674(00)80081-1
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摘要: Abstract The Neurospora crassa Asm-1 + (ascospore maturation 1) gene encodes an abundant nucleus-localized protein required for formation of female structures and ascospore maturation. Deletion mutants are "ascus-dominant," i.e., when crossed to wild type, neither nor Δ spores mature. To explain this behavior, we considered three models: effect reduced dosage the product, failure internuclear communication, transvection (regulation dependent on pairing alleles). We found that proper regulation subsequent sexual sporulation, must be in proximity, probably paired, its allelic counterpart zygote: occur. Disruption causes progeny Transvection Neurospora, unlike Drosophila, occurs immediately before meiosis, can demonstrated between wild-type alleles.