Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome

作者: Magdalena Surman , Ewa Stępień , Małgorzata Przybyło

DOI: 10.3390/PROTEOMES7020021

关键词:

摘要: Malignant melanoma is one of the most aggressive types cancer, and its incidence increasing rapidly each year. Despite extensive research into improved diagnostic treatment methods, early detection disease constraint still present significant challenges. As successful isolation protocols have been developed, extracellular vesicles (EVs) become subject investigation in terms their role cancer progression as a possible source biomarkers. Besides functional studies, quantitative qualitative proteomics recently emerged promising tools for advancement Nevertheless, amount data concerning proteome melanoma-derived EVs very limited. In this review we cover current knowledge on protein content EVs, with focus potential development melanomas.

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