Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage
作者： Jukka Huttunen , Antti Lindgren , Mitja I. Kurki , Terhi Huttunen , Juhana Frösen
DOI: 10.1212/WNL.0000000000004113
关键词:
摘要: Objective: To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors subarachnoid hemorrhage from saccular intracranial aneurysm (SIA-SAH). Methods: The Kuopio SIA Database (kuopioneurosurgery.fi) includes all SIA-SAH patients admitted to University Hospital its defined catchment population in Eastern Finland. study cohort consists 779 patients, 1995 2007, who were alive at 12 months after SIA-SAH. Their use reimbursable antiepileptic drugs (ICD-10) fused Finnish national registries 1994 2014. Results: followed up until (n = 197) or December 31, 2014, a median 12.0 years Epilepsy had been diagnosed 121 (15%) SIA-SAH, 34/121 (28%) died end follow-up, with epilepsy as immediate cause 7/34 (21%). In was an independent risk factor for (hazard ratio 1.8, 95% confidence interval 1.1–3.0). Conclusions: Comorbid is associated increased follow-up. Survivors require dedicated including identification effective treatment comorbid prevent avoidable deaths.
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