The microbiome as a key regulator of brain, behavior and immunity: commentary on the 2017 named series

作者: Michael T. Bailey , John F. Cryan

DOI: 10.1016/J.BBI.2017.08.017

关键词:

摘要: The focus on the microbiome for 2017 Named Series in Brain, Behavior, and Immunity reflects rapidly growing interest commensal microbes effects that they can have physiological processes often studied PsychoNeuroImmunology Research. studies included this show impact immune system activity, as well brain behavioral across lifespan, are involved immunological responses to social stresses. also dietary brain, behavior, immunity involve alterations of gut microbiota. Thus, diet be used therapeutically diseases conditions involving immunity, treatment with both pre- probiotics. While has been widely tested animal models, fewer focused probiotic humans. highlight challenges research human populations, but future promise probiotics health. emotional disorders, such anxiety depression linked microbiota, identify new domains interactions between including schizophrenia, traumatic injury, stroke. As a whole, collection work demonstrates importance regulating key aspects provides important rationale extending so findings translated into clinical practice.

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