Drug—drug interactions that should be non-interruptive in order to reduce alert fatigue in electronic health records

摘要: Objective Alert fatigue represents a common problem associated with the use of clinical decision support systems in electronic health records (EHR). This is particularly profound drug–drug interaction (DDI) alerts for which studies have reported override rates approximately 90%. The objective this study to report consensus-based recommendations an expert panel on DDI that can be safely made non-interruptive provider's workflow, EHR, attempt reduce alert fatigue. Methods We utilized process rate interactions. Panelists had expertise medicine, pharmacy, pharmacology and informatics, represented both academic institutions vendors medication knowledge bases EHR. In addition, representatives from US Food Drug Administration American Society Health-System Pharmacy contributed discussions. Results Recommendations considerations resulted creation list 33 class-based low-priority do not warrant being interruptive one institution, these accounted 36% interactions displayed. Discussion Development customization content drive alerting resource-intensive task. Creation standardized may help across EHR. Conclusions Future efforts might include development consortium maintain over time. Such could also used conjunction financial incentives tied its adoption