Surgical management of exophytic chiasmatic- hypothalamic tumors of childhood

摘要: Sixteen children underwent 18 operations for radical resection of chiasmatic-hypothalamic tumors. The clinical presentation correlated with age: infants under 1 year age presented macrocephaly, failure to thrive, and severe visual failure; aged 5 years predominantly had precocious puberty mild deficits; older (greater than old) slowly progressive loss vision. All three biologically aggressive tumors in spite low-grade histology, died from tumor growth. Eleven the 13 or over are alive well, without radiographic evidence disease progression, 4 months 1/2 following surgery. Six these patients, a follow-up period 10 (mean 27 months), have no adjuvant therapy surgical resection. authors conclude that: 1) can be performed minimal morbidity; 2) may delay time progression postpone need irradiation; 3) postirradiation recurrent provide neurological improvement long-lasting remission; 4) infancy neoplasms that require multimodality therapy.