The role of Area 10 (BA10) in human multitasking and in social cognition: A lesion study

摘要: A role for rostral prefrontal cortex (BA10) has been proposed in multitasking, particular, the selection and maintenance of higher order internal goals while other sub-goals are being performed. BA10 also implicated ability to infer someone else's feelings thoughts, often referred as theory mind. While most data support these views come from functional neuroimaging studies, lesion studies scant. In present study, we compared performance a group frontal patients whose lesions involved BA10, did not affect this area (nonBA10), healthy controls on tests requiring multitasking complex mind judgments. Only with involving showed deficits tasks when control subjects. NonBA10 performed more poorly than an executive function screening tool, particularly measures response inhibition abstract reasoning, suggesting that following cannot be explained by general worsening function. addition, searched correlations between volume damage within different subregions BA10. Significant were found right lateral total volume. These findings stress potential pivotal cognitive functions.