Preoperative serum albumin is associated with mortality and complications after radical cystectomy.

作者: Tullika Garg , Ling Y. Chen , Philip H. Kim , Philip T. Zhao , Harry W. Herr

DOI: 10.1111/BJU.12405

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摘要: Objective To determine the association between preoperative serum albumin and mortality postoperative complications after radical cystectomy urinary diversion. Patients Methods We conducted a retrospective review of 1097 cystectomies performed for treatment bladder cancer 1992 2005. All data were entered prospectively into hospital-based database. We used multivariable logistic regression to assess within 90 days surgery, while controlling patient disease characteristics. Results Low was identified in 14% cohort. Preoperative predictor (adjusted odds ratio [OR] per unit increase albumin: 0.61, 95% confidence interval [CI] 0.42–0.90) 90-day (OR 0.33, CI 0.14–0.75) when sex, race, age-adjusted Charlson score, body mass index, prior history abdominal clinical stage, neoadjuvant chemotherapy. As decreased, risk increased. Conclusions In addition low is significant cystectomy. Serum testing can be identify individuals at high-risk morbidity mortality. Keywords: hypoalbuminemia, complications, neoplasms INTRODUCTION Radical (RC) muscle-invasive major extirpative procedure that associated with mortality. Our group has reported complication rates 64% 30-day 1.5%.[1] Modifiable factors, such as nutrition status, are outcomes other surgical procedures colorectal cardiac surgery.[2, 3] Low albumin, particular, surrogate marker strong multiple disciplines; however, only few small studies have focused on urologic surgery.[4–7] These confirmed RC, but an not been investigated. The objective this study define relationship large cohort patients undergoing RC tertiary center.

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