Association between lncRNA-H19 polymorphisms and hepatoblastoma risk in an ethic Chinese population.
作者： Tianbao Tan , Jiahao Li , Yang Wen , Yan Zou , Jiliang Yang
DOI: 10.1111/JCMM.16124
关键词:
摘要: H19 polymorphisms are associated with increased susceptibility to several cancers; however, their role in hepatoblastoma remains unclear. In this study, we investigated the association between three (rs2839698 G>A, rs3024270 C>G, rs217727 G>A) and 213 patients. The rs2839698 were significantly risk, GG genotype a higher risk of than CC at locus. polymorphism was decreased AG lower genotype. These findings confirmed by combined analysis, stratification analysis revealed that age, gender clinical stage susceptibility. GGG AGG haplotypes compared GCA reference (rs2839698, rs3024270, rs217727). correlated MRPL23-AS1 expression, whereas expression. Overall, rs2839698, Chinese Han population.
sci-hub.st 参考文章(41)
SANAA CHOUFANI, CHERYL SHUMAN, ROSANNA WEKSBERG, Molecular findings in Beckwith-Wiedemann syndrome. American Journal of Medical Genetics Part C-seminars in Medical Genetics. ,vol. 163, pp. 131- 140 ,(2013) , 10.1002/AJMG.C.31363
Feng Yang, Jianwei Bi, Xuchao Xue, Luming Zheng, Kangkang Zhi, Jide Hua, Guoen Fang, Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS Journal. ,vol. 279, pp. 3159- 3165 ,(2012) , 10.1111/J.1742-4658.2012.08694.X
Chao Yang, Ran Tang, Xiang Ma, Younan Wang, Dakui Luo, Zekuan Xu, Yi Zhu, Li Yang, Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the Chinese Han population Oncotarget. ,vol. 6, pp. 15311- 15320 ,(2015) , 10.18632/ONCOTARGET.3840
Erbao Zhang, Wei Li, Dandan Yin, Wei De, Liangjun Zhu, Sanyuan Sun, Liang Han, c-Myc-regulated long non-coding RNA H19 indicates a poor prognosis and affects cell proliferation in non-small-cell lung cancer. Tumor Biology. ,vol. 37, pp. 4007- 4015 ,(2016) , 10.1007/S13277-015-4185-5
Teresa M. Holm, Laurie Jackson-Grusby, Tobias Brambrink, Yasuhiro Yamada, William M. Rideout, Rudolf Jaenisch, Global loss of imprinting leads to widespread tumorigenesis in adult mice Cancer Cell. ,vol. 8, pp. 275- 285 ,(2005) , 10.1016/J.CCR.2005.09.007
S. Chitragar, V. K. Iyer, S. Agarwala, S. D. Gupta, A. Sharma, M. N. Wari, Loss of Heterozygosity on Chromosome 11p15.5 and Relapse in Hepatoblastomas European Journal of Pediatric Surgery. ,vol. 21, pp. 50- 53 ,(2011) , 10.1055/S-0030-1267208
Imad Matouk, Basim Ayesh, Tamar Schneider, Suhail Ayesh, Patricia Ohana, Nathan de-Groot, Abraham Hochberg, Eithan Galun, None, Oncofetal splice-pattern of the human H19 gene. Biochemical and Biophysical Research Communications. ,vol. 318, pp. 916- 919 ,(2004) , 10.1016/J.BBRC.2004.04.117
Lorenzo D'Antiga, Francesca Vallortigara, Umberto Cillo, Enrico Talenti, Massimo Rugge, Lucia Zancan, Patrizia Dall'Igna, Gian Luca De Salvo, Giorgio Perilongo, None, Features predicting unresectability in hepatoblastoma Cancer. ,vol. 110, pp. 1050- 1058 ,(2007) , 10.1002/CNCR.22876
Anil Darbari, Keith M Sabin, Craig N Shapiro, Kathleen B Schwarz, Epidemiology of primary hepatic malignancies in U.S. children Hepatology. ,vol. 38, pp. 560- 566 ,(2003) , 10.1053/JHEP.2003.50375
Wei Gao, Meng Zhu, Hao Wang, Shan Zhao, Di Zhao, Yang Yang, Ze-Mu Wang, Fang Wang, Zhi-Jian Yang, Xiang Lu, Lian-Sheng Wang, Association of polymorphisms in long non-coding RNA H19 with coronary artery disease risk in a Chinese population Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. ,vol. 772, pp. 15- 22 ,(2015) , 10.1016/J.MRFMMM.2014.12.009