作者: Jean Armengaud , Alain Dedieu , Olivier Solques , Jean-Luc Pellequer , Eric Quemeneur
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摘要: Background The cluster of orthologous group COG2042 has members in all sequenced Eukaryota as well many Archaea. The cellular function these proteins ancient origin remains unknown. PSI-BLAST analysis does not indicate a possible link with even remotely-related that have been functionally or structurally characterized. As prototype among orthologs, SSO0551 protein from the hyperthermophilic archaeon Sulfolobus solfataricus was purified to homogeneity for biophysical characterization.