Antibodies to PF4A receptor

作者: Anan Chuntharapai , K. Jin Kim , James Lee , Caroline Hebert

DOI:

关键词:

摘要: cDNAs encoding a class of receptors, including the IL-8 have been identified in human tissue. Recombinantly produced PF4ARs are used preparation and purification antibodies capable binding to diagnostic assays. The advantageously prevention treatment inflammatory conditions.

参考文章(44)
C W Taylor, The role of G proteins in transmembrane signalling. Biochemical Journal. ,vol. 272, pp. 1- 13 ,(1990) , 10.1042/BJ2720001
R. A. Dixon, I. S. Sigal, M. R. Candelore, R. B. Register, W. Scattergood, E. Rands, C. D. Strader, Structural features required for ligand binding to the beta-adrenergic receptor. The EMBO Journal. ,vol. 6, pp. 3269- 3275 ,(1987) , 10.1002/J.1460-2075.1987.TB02645.X
M. Loetscher, T. Geiser, T. O'Reilly, R. Zwahlen, M. Baggiolini, B. Moser, Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. Journal of Biological Chemistry. ,vol. 269, pp. 232- 237 ,(1994) , 10.1016/S0021-9258(17)42339-8
J Lee, R Horuk, G.C. Rice, G.L. Bennett, T Camerato, W.I. Wood, Characterization of two high affinity human interleukin-8 receptors. Journal of Biological Chemistry. ,vol. 267, pp. 16283- 16287 ,(1992) , 10.1016/S0021-9258(18)41997-7
R.B. Gayle, P.R. Sleath, S. Srinivason, C.W. Birks, K.S. Weerawarna, D.P. Cerretti, C.J. Kozlosky, N. Nelson, T. Vanden Bos, M.P. Beckmann, Importance of the amino terminus of the interleukin-8 receptor in ligand interactions. Journal of Biological Chemistry. ,vol. 268, pp. 7283- 7289 ,(1993) , 10.1016/S0021-9258(18)53174-4
Stephen D. Wolpe, Anthony Cerami, Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines. The FASEB Journal. ,vol. 3, pp. 2565- 2573 ,(1989) , 10.1096/FASEBJ.3.14.2687068
R. M. Strieter, Richard M Pope, G. K. Haines, A. E. Koch, J. C. Burrows, H. L. Evanoff, S. L. Kunkel, Synovial tissue macrophage as a source of the chemotactic cytokine IL-8. Journal of Immunology. ,vol. 147, pp. 2187- 2195 ,(1991)
J. Kim, R. Horuk, C.A. Hébert, A. Chuntharapai, M. Smith, T. Colby, Partial functional mapping of the human interleukin-8 type A receptor. Identification of a major ligand binding domain. Journal of Biological Chemistry. ,vol. 268, pp. 18549- 18553 ,(1993) , 10.1016/S0021-9258(17)46662-2