PROGRESSIVE NEUROPATHIC (PERONEAL) MUSCULAR ATROPHY (CHARCOT-MARIE-TOOTH DISEASE)

摘要: THERE seems to be a general feeling among neurologists that one is justified in considering as disease entity the condition variously called "peroneal muscular atrophy of Charcot-Marie-Tooth type," "progressive neuritic atrophy," or "spinal form progressive atrophy." The weight available evidence concerning its etiology, most recently reviewed by England and Denny-Brown,1is favor an affection spinal cord peripheral nerves being primary process, changes secondary; but few autopsy reports are found literature. However, biopsy affected muscles may give information interest, since it now well established histological dystrophies differ certain respects from those occurring diseases involving primarily motor neurons, such amytrophic lateral sclerosis, atrophy, syringomyelia, poliomyelitis.2Brodal Refsum3described