Metastatic calcification induced by hytakerol in rats infected with Plasmodium berghei.

摘要: vitamin D, other derivatives of irradiated ergosterol, and parathyroid hormone induce metastatic calcifications in many organs (Vanderveer, 1931; von Brand et al., 1932; Engel, 1952; Baker 1954; Haas 1958). It is also known that several disease conditions, such as tumors, chronic renal disease, hyperparathyroidism, are associated with abnormal tissue (Eisenstein 1960). More rarely have studies involving parasites been reported. has, however, found structures originating from the host, wall Trichinella cysts (von 1933, 1938; Wantland, 1934, 1935, 1936, 1938), readily calcify under influence above compounds, do tissues degenerating a sequel parasitic invasion, damaged due to larval tapeworm migrating through liver 1933). Parasites, general, seem liable artificial calcification only after they died (Otto Brand, 1941). Still less information available concerning possible infections on experimental production host. Von Holtz (1933) described an increased susceptibility canary birds infected Plasmodium praecox. was considered worth while examine this question further, employing mammalian malaria species, berghei. In present investigation, effects produced by large amounts dihydrotachysterol concentrate organ host were studied during malarial infection rats.