Application of Navigated Transcranial Magnetic Stimulation to Map the Supplementary Motor Area in Healthy Subjects.

摘要: PURPOSE The supplementary motor area is involved in the planning and coordination of movement sequences. This study investigates potential repetitive navigated transcranial magnetic stimulation for systematic mapping by interfering with normal processing. METHODS Ten healthy females (median age: 23.5 years) performed Jebsen-Taylor Hand Function Test, first without (baseline) afterward during application 10 Hz to 6 cortical sites located within both hemispheres. test completion times (TCTs) were then compared between baseline performances stimulation. RESULTS We found significant slowing TCTs simulated page turning (baseline TCT 3.68 ± 0.67 seconds vs. 4.04 0.63 seconds, P = 0.0136), lifting small objects 5.11 0.72 5.47 0.66 0.0010), feeding 6.10 0.73 6.59 0.81 0.0027). Three other subtests not affected, whereas one subtest was significantly faster 17.09 7.31 15.44 5.72 0.0073) under CONCLUSIONS Repetitive capable influencing performance participants a task relying on hand coordination. Our approach can serve as tool area, potentially relevant preoperative diagnostics patients brain tumors, epilepsy, or lesions improve outcome predict clinical course postoperative recovery.