Effect of Medical Treatment of Severe Hypertension

摘要: The classic paper by Keith, Wagener, and Barker1in 1939 as well other studies2-7of the natural course of severe hypertension have shown that prognosis in untreated cases is poor. In series Barker, 79% 145 patients with malignant (group 4) were dead within one year only patient survived for five years after diagnosis was made (Figure). Effective hypotensive drugs been available nearly ten years, but recently has enough experience treatment large groups severely hypertensive over a long period from which efficacy prolonged drug therapy can be evaluated. Several such studies indicate intensive ganglion-blocking agents prolongs life.5-16The current study undertaken an attempt to evaluate effect group 3 4 hypertension,