Synthetic approaches to polypyridyl bridging ligands with proximal multidentate binding sites.

摘要: A series of 12 bridging ligands was prepared. These include a central linker appended to two 1,8-naphthyrid-2-yl or 1,10-phenanthrolin-2-yl units. The linkers pyridazin-3,6-diyl, 1,8-naphthyrid-2,7-diyl, 2,2‘-bipyrid-6,6‘-diyl, 1,10-phenanthrolin-2,9-diyl, 1,2-di(2‘-pyrid-6‘-yl)ethyne, and 3,6-di(2‘-pyrid-6‘-yl)pyridazine. were synthesized from the diacetyl derivative by Friedlander condensation with either 2-aminonicotinaldehyde 8-amino-7-quinolinecarbaldehyde. precursor derivatives were, in turn, prepared pathways involving Stille Sonogashira couplings. Examination electronic absorption spectra shows strongest correlation be between pairs having same linker. Complexation studies will follow.