作者: G.D. Schott , Maria A. Wyke
DOI: 10.1016/0022-510X(77)90127-7
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摘要: Abstract Amongst the abnormal synkinesias, bilateral and obligatory associated movements affecting predominantly hands comprise a group of movement disorders which we have divided into: (1) those occurring as an autosomal dominant hereditary condition; (2) in presence disease central nervous system, including congenital abnormalities cervical region; (3) rare, sporadic cases otherwise healthy individuals. A left-handed patient falling into last is reported, whom detailed neuropsychological assessment was also undertaken. Recalling normal bimanual synkinesias childhood, some mechanisms implicated production pathological are discussed: effect structural lesions within defects motor inhibition role sensory afferent information, part played by commissures pathways, question handedness, relationship to mirror writing, cerebral dominance all been considered relevant, but from increasing evidence available experimental work on primates possible direct corticomotoneuronal connections emphasised.