Protease-activatable cell-penetrating peptide possessing ROS-triggered phase transition for enhanced cancer therapy

作者: Jisang Yoo , N. Sanoj Rejinold , DaeYong Lee , Sangyong Jon , Yeu-Chun Kim

DOI: 10.1016/J.JCONREL.2017.08.026

关键词:

摘要: … MMP-sensitive cleavage and ROS-induced DOX release. Moreover, we confirmed efficient DOX … Furthermore, MLMP (DOX) exhibited outstanding tumor inhibition capability with non-…

参考文章(39)
Earl R. Stadtman, Jackob Moskovitz, Barbara S. Berlett, Rodney L. Levine, Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism Molecular and Cellular Biochemistry. ,vol. 234, pp. 3- 9 ,(2002) , 10.1007/978-1-4615-1087-1_1
Guangzhi Gu, Huimin Xia, Quanyin Hu, Zhongyang Liu, Mengyin Jiang, Ting Kang, Deyu Miao, Yifan Tu, Zhiqing Pang, Qingxiang Song, Lei Yao, Hongzhan Chen, Xiaoling Gao, Jun Chen, PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy. Biomaterials. ,vol. 34, pp. 196- 208 ,(2013) , 10.1016/J.BIOMATERIALS.2012.09.044
Hong-Xia Wang, Xian-Zhu Yang, Chun-Yang Sun, Cheng-Qiong Mao, Yan-Hua Zhu, Jun Wang, None, Matrix metalloproteinase 2-responsive micelle for siRNA delivery. Biomaterials. ,vol. 35, pp. 7622- 7634 ,(2014) , 10.1016/J.BIOMATERIALS.2014.05.050
Michael Schieber, Navdeep S. Chandel, ROS Function in Redox Signaling and Oxidative Stress Current Biology. ,vol. 24, pp. R453- R462 ,(2014) , 10.1016/J.CUB.2014.03.034
Ilkoo Noh, Hyun-Ouk Kim, Jihye Choi, Yuna Choi, Dong Ki Lee, Yong-Min Huh, Seungjoo Haam, Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer. Biomaterials. ,vol. 53, pp. 763- 774 ,(2015) , 10.1016/J.BIOMATERIALS.2015.03.006
Kadi-Liis Veiman, Kadri Künnapuu, Tõnis Lehto, Kristina Kiisholts, Kalle Pärn, Ülo Langel, Kaido Kurrikoff, PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo. Journal of Controlled Release. ,vol. 209, pp. 238- 247 ,(2015) , 10.1016/J.JCONREL.2015.04.038
Mukesh K. Gupta, Travis A. Meyer, Christopher E. Nelson, Craig L. Duvall, Poly(PS-b-DMA) micelles for reactive oxygen species triggered drug release Journal of Controlled Release. ,vol. 162, pp. 591- 598 ,(2012) , 10.1016/J.JCONREL.2012.07.042
Ülo Copolovici, Dana, Langel, Kent, Eriste, Elo, Langel, Cell-Penetrating Peptides : Design, Synthesis, and Applications ACS Nano. ,vol. 8, pp. 1972- 1994 ,(2014) , 10.1021/NN4057269
J. Moskovitz, B. S. Berlett, J. M. Poston, E. R. Stadtman, The yeast peptide-methionine sulfoxide reductase functions as an antioxidant in vivo Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 9585- 9589 ,(1997) , 10.1073/PNAS.94.18.9585
Ning Ma, Ying Li, Huaping Xu, Zhiqiang Wang, Xi Zhang, Dual Redox Responsive Assemblies Formed from Diselenide Block Copolymers Journal of the American Chemical Society. ,vol. 132, pp. 442- 443 ,(2010) , 10.1021/JA908124G