Cloning and characterization of pentylenetetrazol-related cDNA, PTZ-17.
作者： Kagemasa Kajiwara , Eiichi Sugaya , Minoru Kimura , Motoya Katsuki , Hideko Nagasawa
DOI: 10.1016/0006-8993(94)01308-5
关键词:
摘要: cDNAs related to pentylenetetrazol-induced bursting activity in neurons were screened by a differential hybridization method using normal and pentylenetetrazol-treated primary cultured from the cerebral cortex of mice. Twenty clones candidate cDNA with expression increased or decreased treatment pentylenetetrazol obtained. One them, PTZ-17, was sequenced. Injection PTZ-17 derived RNA into Xenopus oocytes showed large calcium inward current extracellular application pentylenetetrazol.
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