Race and Ethnicity Influence Survival Outcomes in Women of Caribbean Nativity With Epithelial Ovarian Cancer

作者: Matthew Schlumbrecht , Danielle Cerbon , Melissa Castillo , Scott Jordan , Raleigh Butler

DOI: 10.3389/FONC.2020.00880

关键词:

摘要: Background: Caribbean immigrants represent one of the largest groups minorities in United States (US), yet are understudied. Racial and ethnic disparities among women with ovarian cancer have been reported, but not immigrant populations. Our objective was to evaluate differences clinicopathologic features survival outcomes Caribbean-born (CB) cancer, special focus on influence race ethnicity these measures. Methods: A review institutional registry performed identify known nativity treated for epithelial between 2005 2017. Sociodemographic, clinical, data were collected. Analyses done using chi-square, Cox proportional hazards models, Kaplan-Meier method, significance set at p < 0.05. Results: 529 included analysis, 248 CB 281 US-born (USB). more likely residual disease after debulking surgery (31.2 vs. 16.8%, = 0.009) be a public facility (62.5 33.5%, 0.001). Black less frequently received chemotherapy compared White (55.2 82.2%, Among all women, Hispanic independently associated improved when adjusting other factors (HR 0.61 [95% CI 0.39-0.95], 0.03). had median overall (OS) 59 months while Black, non-Hispanic OS 24 (log-rank 0.04). Conclusion: is significantly outcomes, regardless race.

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