Síndrome urémico hemolítico atípico en el embarazo

摘要: Atypical haemolytic uraemic syndrome is one of the main variants thrombotic microangiopathy, and characterized by excessive complement activation in microvasculature. It also characterised clinical triad; non-immune anaemia, thrombocytopenia, acute renal failure. In addition, 60% patients have mutations genes encoding regulators (factor H, factor I, membrane cofactor proteins, thrombomodulin), activators B C3), as well autoantibodies against H. Multiple factors are required for disease to manifest itself, including a trigger gene with adequate penetration. Being differential diagnoses preeclampsia- eclampsia HELLP means that clinician must be familiar due its high mortality, which can modified early diagnosis comprehensive treatment.