Cellular senescence and its effector programs

作者: R. Salama , M. Sadaie , M. Hoare , M. Narita

DOI: 10.1101/GAD.235184.113

关键词:

摘要: Cellular senescence is a stress response that accompanies stable exit from the cell cycle. Classically, senescence, particularly in human cells, involves the p53 and p16/Rb pathways …

参考文章(167)
Andrew R. J. Young, Masako Narita, Masashi Narita, Cell senescence as both a dynamic and a static phenotype. Methods of Molecular Biology. ,vol. 965, pp. 1- 13 ,(2013) , 10.1007/978-1-62703-239-1_1
Jacqueline J. L. Jacobs, Karin Kieboom, Silvia Marino, Ronald A DePinho, Maarten van Lohuizen, The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus Nature. ,vol. 397, pp. 164- 168 ,(1999) , 10.1038/16476
Mark Pearson, Roberta Carbone, Carla Sebastiani, Mario Cioce, Marta Fagioli, Shin’ichi Saito, Yuichiro Higashimoto, Ettore Appella, Saverio Minucci, Pier Paolo Pandolfi, Pier Giuseppe Pelicci, PML regulates p53 acetylation and premature senescence induced by oncogenic Ras Nature. ,vol. 406, pp. 207- 210 ,(2000) , 10.1038/35018127
Jerry W. Shay, Woodring E. Wright, Hayflick, his limit, and cellular ageing Nature Reviews Molecular Cell Biology. ,vol. 1, pp. 72- 76 ,(2000) , 10.1038/35036093
Georg Krohne, Ricardo Benavente, The nuclear lamins: A multigene family of proteins in evolution and differentiation Experimental Cell Research. ,vol. 162, pp. 1- 10 ,(1986) , 10.1016/0014-4827(86)90421-0
Christopher J Hutchison, B-type lamins and their elusive roles in metazoan cell proliferation and senescence The EMBO Journal. ,vol. 31, pp. 1058- 1059 ,(2012) , 10.1038/EMBOJ.2012.39
Anitha Suram, Jessica Kaplunov, Priyanka L Patel, Haihe Ruan, Aurora Cerutti, Virginia Boccardi, Marzia Fumagalli, Raffaella Di Micco, Neena Mirani, Resham Lal Gurung, Manoor Prakash Hande, Fabrizio d‧Adda di Fagagna, Utz Herbig, Oncogene‐induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions The EMBO Journal. ,vol. 31, pp. 2839- 2851 ,(2012) , 10.1038/EMBOJ.2012.132
Masashi Narita, Masako Narita, Valery Krizhanovsky, Sabrina Nuñez, Agustin Chicas, Stephen A. Hearn, Michael P. Myers, Scott W. Lowe, A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell. ,vol. 126, pp. 503- 514 ,(2006) , 10.1016/J.CELL.2006.05.052
M. Narita, A. R. J. Young, S. Arakawa, S. A. Samarajiwa, T. Nakashima, S. Yoshida, S. Hong, L. S. Berry, S. Reichelt, M. Ferreira, S. Tavare, K. Inoki, S. Shimizu, M. Narita, Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes Science. ,vol. 332, pp. 966- 970 ,(2011) , 10.1126/SCIENCE.1205407
K. Agger, P. A.C. Cloos, L. Rudkjaer, K. Williams, G. Andersen, J. Christensen, K. Helin, The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A–ARF locus in response to oncogene- and stress-induced senescence Genes & Development. ,vol. 23, pp. 1171- 1176 ,(2009) , 10.1101/GAD.510809