Protein synthesis in liver and skeletal muscle of mice bearing an ascites tumor.

作者: Virginia M. Pain , David P. Randall , Peter J. Garlick

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摘要: Abstract In mice bearing an ascites tumor at advanced stage of growth, the weight gastrocnemius muscle fell, whereas that liver increased. Fractional rates protein synthesis were measured in vivo under conditions designed to minimize uncertainties determination specific radioactivity precursor amino acid pool. Protein increased tumor-bearing comparison with controls either fed ad libitum or pair-fed reduced food intake group. muscle, rate fell substantially -fed but was not significantly different from a group for which restricted animals.

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