Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion

作者: Rada Amin , Claire Carrion , Catherine Decourt , Eric Pinaud , Michel Cogné

DOI: 10.1111/J.1365-2567.2012.03557.X

关键词:

摘要: … transcripts (Iα-Cα), production of which is a prerequisite for CSR, and Iμ-Cα transcripts that are … to α-chain switching; we quantified those transcripts after 3 days of in vitro stimulation. The …

参考文章(24)
C.J. Word, J.F. Mushinski, P.W. Tucker, The murine immunoglobulin alpha gene expresses multiple transcripts from a unique membrane exon. The EMBO Journal. ,vol. 2, pp. 887- 898 ,(1983) , 10.1002/J.1460-2075.1983.TB01518.X
C M Snapper, T M McIntyre, M R Kehry, Novel in vitro model for high-rate IgA class switching. Journal of Immunology. ,vol. 154, pp. 3156- 3161 ,(1995)
Andrew J. S. Macpherson, Alain Lamarre, Kathy McCoy, Gregory R. Harriman, Bernard Odermatt, Gordon Dougan, Hans Hengartner, Rolf M. Zinkernagel, IgA production without μ or δ chain expression in developing B cells Nature Immunology. ,vol. 2, pp. 625- 631 ,(2001) , 10.1038/89775
J F Elliott, V Paetkau, W Strober, G R Harriman, D Y Kunimoto, The role of IL-5 in IgA B cell differentiation. Journal of Immunology. ,vol. 140, pp. 3033- 3039 ,(1988)
M Cogné, J L Preud'homme, Gene deletions force nonsecretory alpha-chain disease plasma cells to produce membrane-form alpha-chain only. Journal of Immunology. ,vol. 145, pp. 2455- 2458 ,(1990)
M A Kerr, The structure and function of human IgA Biochemical Journal. ,vol. 271, pp. 285- 296 ,(1990) , 10.1042/BJ2710285
Milena Hasan, Bojan Polic, Marina Bralic, Stipan Jonjic, Klaus Rajewsky, Incomplete block of B cell development and immunoglobulin production in mice carrying the muMT mutation on the BALB/c background. European Journal of Immunology. ,vol. 32, pp. 3463- 3471 ,(2002) , 10.1002/1521-4141(200212)32:12<3463::AID-IMMU3463>3.0.CO;2-B
Per Brandtzaeg, Inger Nina Farstad, Finn-Eirik Johansen, H. Craig Morton, Inger Natvig Norderhaug, Takeshi Yamanaka, Per Brandtzaeg, Inger Nina Farstad, Finn-Eirik Johansen, H. Craig Morton, Inger Natvig Norderhaug, Takeshi Yamanaka, The B-cell system of human mucosae and exocrine glands. Immunological Reviews. ,vol. 171, pp. 45- 87 ,(1999) , 10.1111/J.1600-065X.1999.TB01342.X
John G. Flanagan, Marie-Paule Lefranc, Terence H. Rabbitts, Mechanisms of divergence and convergence of the human immunoglobulin α1 and α2 constant region gene sequences Cell. ,vol. 36, pp. 681- 688 ,(1984) , 10.1016/0092-8674(84)90348-9