Laboratory evolution of an alcohol dehydrogenase towards enantioselective reduction of difficult-to-reduce ketones

作者: Ge Qu , Beibei Liu , Yingying Jiang , Yao Nie , Huilei Yu

DOI: 10.1186/S40643-019-0253-9

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摘要: A thermostable alcohol dehydrogenase from Thermoanaerobacter brockii (TbSADH) has been repurposed to perform asymmetric reduction of a series of prochiral ketones with the …

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