Total ssynthesis of (±) thiolactomycin☆
作者： Chia-Lin J. Wang , J.M Salvino
DOI: 10.1016/S0040-4039(01)81574-4
关键词:
摘要: Abstract We have completed the first total synthesis of (±)-thiolactomycin by a five-step procedure in 10% overall yield starting from ketoester 6. The key step involves addition dianion 3 to 3-ethoxy-2-methyl-2-propenal. resulting aldehyde 11 was then converted into (±)-thiolactomycin.
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