Behavior of Biozzi high and low responder mice upon infection with Schistosoma mansoni.

摘要: Mice genetically selected for high (Ab/H) or low (Ab/L) humoral antibody responses were infected with Schistosoma mansoni in order to assess the role of antibodies innate and acquired immunity this parasite. Ab/H mice produced higher levels schistosome antigens, but more susceptible infection than Ab/L mice. This was shown by number parasites recovered from mice, larger size themselves, eggs their rate deposition host liver. In addition, could develop an resistance re-infection which as good as, possibly even better developed These findings suggest that per se may not play a critical immunity, at same time call attention possible importance macrophages determining results observed.