A Depression in Left Ventricular Diastolic Filling following Prolonged Strenuous Exercise is Associated with Changes in Left Atrial Mechanics

摘要: Background Standard marathon running can result in a depression of left ventricular (LV) diastolic function during early recovery. Left atrial (LA) mechanics are integral maintaining an pressure gradient as well being responsive to changes LV function, and therefore the detailed assessment LA may provide further insight. The aim this study was determine impact prolonged strenuous exercise on atrium association with function. Methods Myocardial speckle-tracking echocardiograms ventricle were obtained prior to, immediately after, 6 hours after completion (42.2 km) 17 healthy adult men. Speckle tracking used peak deformation, deformation rate, contractile including activation time. volumes throughout cardiac cycle also assessed reservoir, conduit, booster pump volumes. Diastolic included strain late standard indices. Temporal "twist" "untwist" evaluated. Results All subjects completed (mean finishing time, 209 ± 19 minutes; range, 173-241 minutes). Although significantly increased, there reduction rate that correlated reduced deformation. Atrial time increased race. indices diastole, whereas torsion at end-systole elevated isovolumic period returned toward baseline exercise. Conclusions This demonstrates transient relaxation following appear have direct subsequent preload these findings delay requires exploration.