Marine Sponges – Molecular Biology and Biotechnology

作者: ADW Dobson , Stephen A. Jackson , , Jonathan Kennedy , Lekha Menon Margassery

DOI: 10.1007/978-3-642-53971-8_8

关键词:

摘要: Marine sponges are an ancient and diverse animal phylum that host well-established symbiotic microbial communities. The vast majority of the genetic diversity in is, however, currently inaccessible by traditional methods. This large resource may be use for biotechnological applications, particularly as physicochemical parameters under which genes within these microbes function likely to dictate they significantly different from similar or gene products industry, offering some instances improved performance. Emerging tools technologies field metagenomics offer enormous potential discovery exploitation new biosynthetic entities. Both sequence-based function-based have date been employed identify with novel functions. sponges, well-recognized sources marine natural varied ideal target implementation technologies. We detail here successes development industrial pharmaceutical applications we also highlight technical impediments product yet still need overcome.

参考文章(279)
Anthony R. Carroll, Malcolm S. Buchanan, Annette Edser, Edward Hyde, Moana Simpson, Ronald J. Quinn, Dysinosins B-D, inhibitors of factor VIIa and thrombin from the Australian sponge Lamellodysidea chlorea. Journal of Natural Products. ,vol. 67, pp. 1291- 1294 ,(2004) , 10.1021/NP049968P
Hua Zhang, Melissa M. Conte, Xiao-Cong Huang, Zeinab Khalil, Robert J. Capon, A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp. Organic and Biomolecular Chemistry. ,vol. 10, pp. 2656- 2663 ,(2012) , 10.1039/C2OB06747A
Tetsuro Yasuda, Atsushi Araki, Takaaki Kubota, Junji Ito, Yuzuru Mikami, Jane Fromont, Jun’ichi Kobayashi, Bromopyrrole alkaloids from marine sponges of the genus Agelas. Journal of Natural Products. ,vol. 72, pp. 488- 491 ,(2009) , 10.1021/NP800645Q
Anthony R. Carroll, Sonya M. Kaiser, Rohan A. Davis, Roger W. Moni, John N. A. Hooper, Ronald J. Quinn, A Bastadin with Potent and Selective δ-Opioid Receptor Binding Affinity from the Australian Sponge Ianthella flabelliformis Journal of Natural Products. ,vol. 73, pp. 1173- 1176 ,(2010) , 10.1021/NP100010Z
Jason B. Sylvan, Brandy M. Toner, Katrina J. Edwards, Life and Death of Deep-Sea Vents: Bacterial Diversity and Ecosystem Succession on Inactive Hydrothermal Sulfides Mbio. ,vol. 3, pp. 1- 10 ,(2012) , 10.1128/MBIO.00279-11
Martin Pfannkuchen, Sabine Schlesinger, Alexander Fels, Franz Brümmer, Microscopical techniques reveal the in situ microbial association inside Aplysina aerophoba, Nardo 1886 (Porifera, Demospongiae, Verongida) almost exclusively consists of cyanobacteria Journal of Experimental Marine Biology and Ecology. ,vol. 390, pp. 169- 178 ,(2010) , 10.1016/J.JEMBE.2010.04.038
Erik L. Regalado, Deniz Tasdemir, Marcel Kaiser, Nadja Cachet, Philippe Amade, Olivier P. Thomas, Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. Journal of Natural Products. ,vol. 73, pp. 1404- 1410 ,(2010) , 10.1021/NP100348X
Crystal Richardson, Malcolm Hill, Carolyn Marks, Laura Runyen-Janecky, April Hill, Experimental manipulation of sponge/bacterial symbiont community composition with antibiotics: sponge cell aggregates as a unique tool to study animal/microorganism symbiosis FEMS Microbiology Ecology. ,vol. 81, pp. 407- 418 ,(2012) , 10.1111/J.1574-6941.2012.01365.X
Luiz Duarte, Rosebel Nalesso, The SpongeZygomycale parishii(Bowerbank) and its Endobiotic Fauna Estuarine Coastal and Shelf Science. ,vol. 42, pp. 139- 151 ,(1996) , 10.1006/ECSS.1996.0011
Doris Steger, Piers Ettinger-Epstein, Stephen Whalan, Ute Hentschel, Rocky de Nys, Michael Wagner, Michael W. Taylor, Diversity and mode of transmission of ammonia-oxidizing archaea in marine sponges Environmental Microbiology. ,vol. 10, pp. 1087- 1094 ,(2008) , 10.1111/J.1462-2920.2007.01515.X