Limb Salvage and Amputation in Survivors of Pediatric Lower-Extremity Bone Tumors: What Are the Long-Term Implications?

摘要: The past four decades have seen tremendous progress in the treatment of pediatric and adolescent cancers. As a consequence, there are increasing numbers adult childhood cancer survivors. This has prompted investigation into long-term consequences treatments. One group that merits special study is survivors lower-extremity bone tumors. Their function quality life may depend part on both surgery age at which it was performed. Comparisons between studies difficult because small patients use varying research designs methods limited this area. purpose article to review major surgical approaches lower-limb tumors their impact patients. results show survival equivalent amputation limb salvage. Complications occur more frequently outcomes those undergoing salvage not been found be substantially different regard life. In conclusion, prospective follow-up with needed (1) determine uniform manner complications, life, functionality population describe differences within patient based diagnosis procedure, (2) identify areas concern amenable intervention, (3) provide clinicians future better understanding options.